Speakers 2021

Speakers 2021

Stephane DEPIL

Léon Bérard Cancer Center


Prof. Stéphane Depil, M.D., Ph.D., is onco-hematologist at Léon Bérard Cancer Center, group leader at Cancer Research Center of Lyon, and adjunct Professor at University Claude Bernard Lyon 1, France. He was also Visiting Professor at King’s College London. He is the founder and chairman of ErVaccine Technologies. He received his M.D. from Lille University School of Medicine and obtained a Ph.D. in immunology at Institute of Biology of Lille after working on a project of cancer vaccination. Stéphane Depil has over 15 years of experience in oncology development, both in academic centers and pharmaceutical companies. He was Senior Vice President Research and Development and Chief Medical Officer at Cellectis and served as Chief Executive Officer at Netris Pharma. Prior to Netris, Stéphane Depil worked at Servier Research Institute for 8 years in a variety of roles, including Director of Oncology Research and Development. He is the author of more than 100 articles and abstracts and co-inventor of more than 10 patents   T cell-based therapies in solid tumors: challenges and perspectives TCR engineered and CAR T cell therapies represent two complementary approaches in the treatment of solid tumors. We will discuss the pros and cons of these two technologies and the obstacles posed by the tumor microenvironment in solid tumors, such as immunosuppression and poor T cell trafficking. We will provide an overview of the emerging strategies that are developed to engineer safer and more effective T cell-based immunotherapies as well as examples of new targets.  

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